Nuclear Decay and Radioactivity (4E)

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MCAT Chemical and Physical Foundations of Biological Systems › Nuclear Decay and Radioactivity (4E)

Questions 1 - 10
1

A radiopharmacy prepares $^{125}\text{I}$ seeds for brachytherapy; $^{125}\text{I}$ decays by electron capture to $^{125}\text{Te}$. The half-life is 59 days. Two identical sealed seeds are stored: Seed 1 is stored for 59 days; Seed 2 is stored for 118 days. What prediction can be made about the decay rate (activity) of Seed 2 relative to Seed 1 at the time of use, assuming identical initial activity?

Seed 2 has twice the activity of Seed 1 because the decay constant is unchanged.

Seed 2 has one-quarter the activity of Seed 1 because one additional half-life has elapsed.

Seed 2 has the same activity as Seed 1 because electron capture does not change mass number.

Seed 2 has half the activity of Seed 1 because one additional half-life has elapsed.

Explanation

This question tests understanding of nuclear decay and radioactivity, specifically the concept of half-life and activity calculations. After one half-life (59 days), Seed 1 will have half its original activity. After two half-lives (118 days), Seed 2 will have undergone two halvings: (1/2) × (1/2) = 1/4 of its original activity. Since both seeds started with identical initial activity, Seed 2 will have half the activity of Seed 1 at their respective times of use. Choice A is correct because Seed 2 has experienced one additional half-life compared to Seed 1. Choice D is incorrect because it compares Seed 2's activity to the original activity rather than to Seed 1's activity at 59 days.

2

A researcher labels red blood cells with $^{51}\text{Cr}$ to track cell survival. $^{51}\text{Cr}$ decays primarily by electron capture to $^{51}\text{V}$ with a half-life of 27.7 days (decay constant $\lambda \approx 2.9\times 10^{-7}\ \text{s}^{-1}$). Which statement best describes the decay process illustrated?

The nucleus emits a helium nucleus, decreasing mass number by 4 and atomic number by 2.

A neutron converts to a proton, increasing atomic number by 1 while mass number remains unchanged.

A proton converts to a neutron, decreasing atomic number by 1 while mass number remains unchanged.

The nucleus emits a gamma photon, decreasing mass number by 1 while atomic number is unchanged.

Explanation

This question tests understanding of nuclear decay and radioactivity, specifically electron capture. In electron capture, a proton in the nucleus captures an inner orbital electron and converts to a neutron, emitting a neutrino. When Cr-51 undergoes electron capture to V-51, the atomic number decreases by 1 (from 24 for chromium to 23 for vanadium) while the mass number remains at 51. Choice A is correct as it accurately describes the conversion of a proton to a neutron and the resulting decrease in atomic number. Choice B is incorrect because it describes beta-minus decay (neutron to proton conversion), which is the opposite process.

3

A laboratory prepares a sealed standard containing $^{60}\text{Co}$, which decays by $\beta^-$ emission to an excited state of $^{60}\text{Ni}$ followed by gamma emission. The half-life of $^{60}\text{Co}$ is 5.27 y. Based on the decay model, what outcome is most likely regarding the sequence of emissions?

Gamma emission changes the element, and subsequent beta emission relaxes the nucleus without changing identity

Beta emission changes the element, and subsequent gamma emission relaxes the daughter nucleus without changing its identity

Beta emission decreases mass number by 4, and gamma emission decreases mass number by 1

Gamma emission must occur before beta emission because photons are faster than electrons

Explanation

This question tests understanding of sequential nuclear decay processes. In ⁶⁰Co decay, β- emission occurs first, converting ⁶⁰Co to ⁶⁰Ni* (excited state) by changing a neutron to proton, thus changing the element. The excited ⁶⁰Ni* then undergoes gamma decay to ground state ⁶⁰Ni, releasing energy without changing nuclear composition. Choice A correctly describes beta emission changing the element followed by gamma emission relaxing the daughter nucleus. Choice B reverses the sequence impossibly, choice C gives incorrect mass changes, and choice D incorrectly relates emission order to particle speed. When analyzing decay chains, beta decay changes element identity while subsequent gamma decay only changes energy state.

4

A research lab labels antibodies with $^{131}\text{I}$ for a targeted therapy model. Assume $^{131}\text{I}$ undergoes $\beta^-$ decay to $^{131}\text{Xe}$. The decay constant is $\lambda = 1.0\times 10^{-6}\ \text{s}^{-1}$. Based on the decay model, what is most consistent with conservation laws for the nuclear reaction?

Mass number increases by 1 and atomic number decreases by 1, with a positron emitted

Mass number remains 131 and atomic number increases by 1, with an electron emitted

Mass number decreases by 1 and atomic number remains constant, with a neutron emitted

Mass number decreases by 4 and atomic number decreases by 2, with an alpha particle emitted

Explanation

This question tests understanding of beta-minus decay and conservation laws. In β- decay of ¹³¹I to ¹³¹Xe, a neutron converts to a proton: n → p + e- + ν̄e. This increases atomic number from 53 (iodine) to 54 (xenon) while mass number remains 131, conserving baryon number. An electron is emitted to conserve charge. Choice A correctly describes mass number conservation at 131, atomic number increase by 1, and electron emission. Choice B incorrectly suggests neutron emission, choice C describes alpha decay, and choice D is physically impossible. When verifying nuclear reactions, check that mass number, charge, and baryon number are conserved on both sides of the equation.

5

A patient receives a therapeutic radionuclide that decays by alpha emission. The clinician notes that alpha particles have high linear energy transfer and short range in tissue. Which statement best describes what must be true about the nuclear change in alpha decay?

The nucleus gains 2 protons and 2 neutrons, increasing atomic number by 2 and mass number by 4

The nucleus loses 2 protons and 2 neutrons, decreasing atomic number by 2 and mass number by 4

The nucleus loses 1 proton and gains 1 neutron, decreasing atomic number by 1 with no mass change

The nucleus remains unchanged because alpha particles are emitted from the electron cloud

Explanation

This question tests understanding of alpha decay and its nuclear changes. Alpha particles are helium-4 nuclei (²He⁴) containing 2 protons and 2 neutrons. When emitted, the parent nucleus loses these 4 nucleons, decreasing atomic number by 2 and mass number by 4. This explains alpha particles' high mass and charge, leading to high linear energy transfer and short tissue range. Choice A correctly describes the loss of 2 protons and 2 neutrons with corresponding decreases in atomic and mass numbers. Choice B incorrectly suggests gaining nucleons, choice C describes a different process, and choice D incorrectly places alpha emission outside the nucleus. When analyzing alpha decay, remember the emitted particle is a complete helium nucleus.

6

A PET tracer sample contains $^{18}\text{F}$ with half-life 110 min. The sample is transported for 220 min before use. Based on the decay model, what outcome is most likely for the remaining activity (ignoring biological clearance)?

About 25% remains because two half-lives have elapsed

About 75% remains because two half-lives remove only one quarter

About 50% remains because half-life depends on initial activity

About 12.5% remains because three half-lives have elapsed

Explanation

This question tests understanding of radioactive decay over multiple half-lives. With t₁/₂ = 110 min and transport time = 220 min, exactly 2 half-lives have elapsed (220/110 = 2). After one half-life, 50% remains; after two half-lives, 25% remains. The formula is: fraction remaining = (1/2)^(t/t₁/₂) = (1/2)² = 1/4 = 25%. Choice A correctly identifies that 25% remains after two half-lives. Choice B incorrectly ignores time dependence, choice C miscalculates the fraction, and choice D incorrectly counts three half-lives. When calculating remaining activity, always determine the number of half-lives as t/t₁/₂ and apply $(1/2)^n$.

7

A sealed source undergoes gamma decay from an excited nuclear state with decay constant $\lambda = 5.0\times 10^{-2}\ \text{s}^{-1}$. Based on the decay model, what outcome is most likely regarding the emitted radiation and nuclear composition?

A photon is emitted and the nucleus retains the same numbers of protons and neutrons

A helium nucleus is emitted and the nucleus loses two protons and two neutrons

A positron is emitted and the nucleus gains one neutron while losing one proton

An electron is emitted and the nucleus gains one proton while losing one neutron

Explanation

This question tests understanding of gamma decay characteristics. Gamma decay involves emission of a high-energy photon from an excited nucleus transitioning to a lower energy state. Unlike particle emission, gamma decay doesn't change the number of protons or neutrons, so both atomic number and mass number remain constant. The nucleus retains its identity but loses energy. Choice A correctly describes photon emission with unchanged nuclear composition. Choice B describes β- decay, choice C describes alpha decay, and choice D describes β+ decay. When analyzing gamma decay, remember it's purely an energy transition without changing nuclear constituents.

8

A sealed sample of a radioisotope used in thyroid imaging has decay constant $\lambda = 0.0866\ \text{h}^{-1}$. Based on the decay model, what prediction can be made about its half-life?

The half-life is approximately 8 h because $t_{1/2}=\ln 2/\lambda$

The half-life cannot be estimated from $\lambda$ without knowing the initial activity

The half-life is approximately 12 h because $t_{1/2}=\lambda/\ln 2$

The half-life is approximately 1 h because half-life equals the inverse of atomic number

Explanation

This question tests understanding of half-life calculation from decay constant. The relationship is t₁/₂ = ln(2)/λ, where ln(2) ≈ 0.693. With λ = 0.0866 h⁻¹, t₁/₂ = 0.693/0.0866 ≈ 8.0 h. This follows directly from the exponential decay law where half the nuclei decay when e^(-λt₁/₂) = 1/2. Choice A correctly calculates half-life as approximately 8 h using t₁/₂ = ln(2)/λ. Choice B incorrectly inverts the formula, choice C gives an arbitrary result, and choice D incorrectly claims initial activity is needed. When calculating half-life from decay constant, always use t₁/₂ = ln(2)/λ ≈ 0.693/λ.

9

A radiotracer undergoes $\beta^-$ decay in vivo. The emitted electron is detected indirectly via downstream instrumentation. Which statement best describes the decay process illustrated in terms of nucleon number conservation?

Mass number decreases by 1 because the emitted electron carries away one nucleon

Both mass number and atomic number remain unchanged because beta particles are photons

Mass number is conserved while atomic number increases by 1 due to neutron-to-proton conversion

Atomic number decreases by 1 because a proton converts to a neutron and emits an electron

Explanation

This question tests understanding of beta-minus decay and nucleon conservation. In β- decay, a neutron converts to a proton (n → p + e- + ν̄e), increasing atomic number by 1 while mass number remains constant since the total number of nucleons (protons + neutrons) is unchanged. The emitted electron is not a nucleon and doesn't affect mass number. Choice A correctly describes mass number conservation with atomic number increase due to neutron-to-proton conversion. Choice B incorrectly suggests mass number decrease, choice C reverses the process, and choice D incorrectly identifies beta particles as photons. When analyzing β- decay, remember that nucleon number (mass number) is conserved while proton number (atomic number) increases by 1.

10

A beta-minus emitter is used to label a metabolite in a cell culture. The nuclear transformation is $n \rightarrow p + e^- + \bar{\nu}_e$. Which statement best describes the decay process illustrated?

The atomic number decreases by 1 while the mass number remains unchanged

The atomic number increases by 1 while the mass number remains unchanged

The mass number decreases by 4 while the atomic number decreases by 2

Both atomic number and mass number remain unchanged because a neutrino carries the charge

Explanation

This question tests understanding of beta-minus decay at the nucleon level. The transformation n → p + e- + ν̄e shows a neutron converting to a proton, which increases the atomic number by 1 (gaining a proton) while mass number remains unchanged (total nucleons constant). The emitted electron carries away negative charge to conserve charge. Choice A correctly describes atomic number increase by 1 with unchanged mass number. Choice B reverses the process, choice C describes alpha decay, and choice D incorrectly assigns charge to the neutrino. When analyzing β- decay, remember it always involves neutron-to-proton conversion, increasing atomic number by 1.

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