0%
0 / 15 answered
Enzyme Inhibition and Regulation (5E) Practice Test
•15 QuestionsQuestion
1 / 15
Q1
A mitochondrial enzyme is assayed for conversion of substrate S to product P. Baseline: $K_m = 0.25\ \text{mM}$, $V_{max} = 30\ \mu\text{M},\text{min}^{-1}$. Inhibitor M increases $K_m,app$ to $1.0\ \text{mM}$ with $V_{max}$ unchanged, while inhibitor N decreases $V_{max,app}$ to $15\ \mu\text{M},\text{min}^{-1}$ with $K_m$ unchanged. Which statement best describes how increasing S would differentially affect inhibition by M versus N?
A mitochondrial enzyme is assayed for conversion of substrate S to product P. Baseline: $K_m = 0.25\ \text{mM}$, $V_{max} = 30\ \mu\text{M},\text{min}^{-1}$. Inhibitor M increases $K_m,app$ to $1.0\ \text{mM}$ with $V_{max}$ unchanged, while inhibitor N decreases $V_{max,app}$ to $15\ \mu\text{M},\text{min}^{-1}$ with $K_m$ unchanged. Which statement best describes how increasing S would differentially affect inhibition by M versus N?