Thermodynamics and Energy Changes (5E) Practice Test

A researcher cools a $100\ \text{g}$ tissue sample (assume $c = 3.5\ \text{J},\text{g}^{-1},^{\circ}\text{C}^{-1}$) from $37^{\circ}\text{C}$ to $35^{\circ}\text{C}$ by placing it in contact with a cold plate. Using heat exchange reasoning, which statement is most consistent with the sign of $q$ for the tissue sample?

A researcher measures the standard Gibbs free energy change for ATP hydrolysis in a buffered aqueous solution at $25^\circ\text{C}$: $\Delta G^\circ' = -30.5\ \text{kJ/mol}$. The solution contains initially 1 mM ATP, 1 mM ADP, and 1 mM $\mathrm{P_i}$, and pH is held constant. This question tests reaction spontaneity via Gibbs free energy. How does the concept of Gibbs free energy apply to this biochemical reaction under these conditions?