Hazardous And Nonhazardous Drugs Practice Test

In an outpatient rheumatology clinic, a 45-year-old female (68 kg) with rheumatoid arthritis is prescribed methotrexate 15 mg PO once weekly and folic acid 1 mg PO daily. Current medications include ibuprofen 400 mg PO PRN pain; PMH: GERD; allergies: sulfa (hives). The clinic nurse asks what PPE is needed when splitting tablets or handling a dropped tablet during medication administration because methotrexate is a hazardous drug. What personal protective equipment is necessary for administering this drug?

In an inpatient hospital unit, a 73-year-old female (60 kg) is receiving warfarin 5 mg PO daily for atrial fibrillation and is newly started on trimethoprim/sulfamethoxazole (TMP/SMX) DS 1 tablet PO twice daily for 7 days for a urinary tract infection. Current medications also include metoprolol succinate 50 mg PO daily; PMH: CKD stage 3; allergies: none. The pharmacist is reviewing the order set for safety and interaction management. What is the most significant safety consideration for this medication?