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Example Questions
Example Question #1 : Understanding The Cell Membrane
Living in Arizona, you see a variety of animals that are able to survive in very hot conditions. One of the ways they are able to tolerate such warm conditions is by maintaining the fluidity of their plasma membranes.
How would a desert tortoise's plasma membrane differ from the plasma membrane of a dog that lives in an air conditioned house?
The tortoise would have more cholesterol in its membrane compared to the dog.
The tortoise would have more unstaurated fatty acid tails in its membrane compared to the dog.
The tortoise would have shorter fatty acid tails in its membrane compared to the dog.
The tortoise would have less phospholipids in its bilayer compared to the dog.
The tortoise would have more cholesterol in its membrane compared to the dog.
The plasma membrane is able to maintain the appropriate level of fluidity by manipulating a variety of factors. More cholesterol in the membrane reduces its permeability, which is useful in hot conditions. Desert animals would also be expected to have very few unstaurated fatty acids, and the fatty acid tails would be longer. All of these factors would help the plasma membrane not be too fluid in the hot sun.
Example Question #2 : Understanding The Cell Membrane
Which form of cellular transport is required to move a molecule against its concentration gradient?
Diffusion
Active transport
Facilitated diffusion
Osmosis
Active transport
The natural flow of molecules is from areas of high concentration to areas of low concentration. To act against this gradient, energy must be input. Active transport requires the use of energy to move a molecule up its concentration gradient. Diffusion, osmosis, and facilitated diffusion are forms of passive transport that move a molecule down its concentration gradient.
Example Question #3 : Understanding The Cell Membrane
Which of the following forms of transport uses vesicles to transport large molecules?
Osmosis
Facilitated diffusion
Endocytosis
Active transport
Endocytosis
Endocytosis involves the use of vesicles to transport large molecules into the cell. Facilitated diffusion, osmosis, and active transport use diffusion or protein channels to transport molecules.
Note that exocytosis also uses vesicles, but uses them to export large molecules out of the cell or to incorporate them into the cell membrane.
Example Question #4 : Understanding The Cell Membrane
How are integral proteins introduced into the cellular membrane of an eukaryotic cell?
Endocytosis brings in the necessary proteins and incorporates them into the membrane
Exocytosis supplies the membrane with the necessary proteins, which are present on the secretory vesicle
Cells have all of the necessary membrane proteins upon completing mitosis
Cytoplasmic ribosomes translate the necessary proteins and send them to the membrane
Exocytosis supplies the membrane with the necessary proteins, which are present on the secretory vesicle
Exocytosis allows the membrane of secretory vesicles to be incorporated into the cellular membrane. This expands the membrane surface, while including the desired proteins into the membrane. Due to fluidity and the mosaic model of the membrane, these proteins can then distribute to other areas on the cell surface.
Endocytosis does the opposite process, and involves a pinching off of the cell membrane in order to transport incoming materials. Ribosomes translate the proteins, however, processing of membrane proteins occurs in the endoplasmic reticulum and Golgi body, ultimately packaging membrane proteins in secratory vesicles for exocytosis.
Example Question #5 : Understanding The Cell Membrane
Where would aspartic acid, an amino acid with a negatively charged side chain, most likely be found in a transmembrane protein?
Outside or inside the cell
Outside the cell
Within the membrane interior, outside the cell, or inside the cell
Within the membrane interior
Inside the cell
Outside or inside the cell
Any amino acid with a charged side chain will be polar. Membranes have hydrophobic tails on the interior, and hydrophilic heads facing the outside and inside of the cell. Since polar molecules are charged, they will interact with the hydrophilic parts of the environment, and therefore they will not be found within the membrane interior.
Example Question #6 : Understanding The Cell Membrane
What would happen to a cell that contains 4.0 moles of solute inside it if it were placed in a cup of water with 2.0 moles of sodium chloride?
It would shrivel
Nothing
Half of the NaCl would move into the cell to make even concentrations
It would burst
It would swell
Nothing
This question is tricky because we need to remember that if there are 2.0 moles of NaCl in the water, then there are 4.0 moles of solute because it will dissociate to one and one ; therefore, this is an isotonic environment and there will be no net movement of water. When a compound dissociates in solution, it is the ion concentration that will affect the movement of water, rather than the amount of initial solid.
Example Question #7 : Understanding The Cell Membrane
The negative charge inside cells is primarily maintained by __________.
the plasma membrane being impermeable to water
the membrane being less permeable to potassium ions than to sodium ions
the sodium-potassium pump
the membrane being less permeable to sodium ions than to potassium ions
the sodium-potassium pump
If there was no expenditure of energy when determining the voltage across the plasma membrane, there would be equal electrical charge on both sides of the bilayer as the ions travel to reach equilibrium. This means that ATP must be used in order to establish a resting potential, keeping the ions away from electrical equilibrium.
The sodium-potassium pump is an example of how ions can be pumped against their electrochemical gradients in order to establish a negative voltage inside the cell. The cell membrane is not permeable to sodium or potassium.
Example Question #8 : Understanding The Cell Membrane
Of the following, which is most likely to pass through the cell membrane via passive transport?
Water, when traveling from a highly hypertonic environment into a cell
A peptide hormone
Glucose
A charged ion
A steroid molecule
A steroid molecule
Passive transport is simple diffusion, without the aid of any protein channels. Since the plasma membrane is composed of a lipid bilayer, the molecules that most readily cross it are small and hydrophobic.
Remember that water is polar; hydrophobic molecules are nonpolar, like lipids and oils. Steroids are derived from cholesterol and are extremely lipid-soluble, so they can cross the membrane unassisted. Large, polar molecules (such as glucose or peptides) and charged ions need channel proteins to facilitate their crossing. Water can diffuse across the membrane, but only when it is moving down its concentration gradient. The answer choice given has water moving from a hypertonic (high-solute, or low-water) environment into a cell, which cannot occur passively.
Example Question #9 : Understanding The Cell Membrane
What is the major factor limiting the size of a cell?
Ratio of surface area to volume
Availability of nutrients
Concentration of water in the cytoplasm
Number of membrane-bound organelles
Ratio of surface area to volume
While the availability of nutrients is a tempting answer, it is important to remember that even in incredibly nutrient-rich environments cells reach a maximum size. The concentration of water in the cytoplasm and the amount of membrane bound organelles will not really have any effect on the size of the cells.
The correct answer is the surface area to volume ratio because it dictates the amount of chemical activity carried out per unit of time. The volume of the cell determines its metabolic needs: larger cells hold more biological material and require more energy and maintenance. The surface area of the cell determines its ability to transport nutrients and absorb nutrients, providing the tools to maintain the cell's volume. A large surface area to volume ratio is essential for the cell.
Example Question #10 : Understanding The Cell Membrane
What are the main components of a phospholipid?
Two fatty acids, a glycerol backbone, and a cholesterol molecule
Three fatty acids and a glycerol backbone
A polar head group, two fatty acids, and a glycerol backbone
A polar head group, two fatty acids, and a glycogen backbone
A polar head group, two fatty acids, and a glycerol backbone
Phospholipids found in the plasma membrane are comprised of a polar head group, two fatty acids, and a glycerol backbone. The phosphate group carries a negative charge, allowing it to interact with polar aqueous environments. The two fatty acid tails form the hydrophobic region of the bilayer interior. The glycerol backbone forms the structural component for linking the polar and non-polar regions.
Glycogen is a polymer of glucose sugars, and is not found in phospholipids. Triglycerides are composed of three fatty acids and a glycerol backbone.
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