We know that the "innervation of the muscle is unaffected" in muscular dystrophy patients, so we are looking for the answer choice that is true of healthy muscle. A neuromuscular junction consists of one neuron and all the muscle fibers it innervates (not just one). The basal lamina does not interfere with action potentials; it just helps the fibers contract together by forming physical connections between fibers. The sarcoplasmic reticulum releases Ca²⁺, not Na⁺. Finally, epinephrine is not the neurotransmitter used at neuromuscular junctions.

All neuron-muscle interactions use acetylcholine as the neruotransmitter, thus vesicles at the neuromuscular junction will contain acetylcholine.

The muscle fiber cytoplasm is the sarcoplasm. The outer covering of the muscle body is the epimysium. The region of the muscle closest to the tendon and the region of sarcolemma near the synapse do not have technical names that you need to know for the MCAT, nor do they make sense as answer choices; we are looking for something that the sarcolemma must be anchored to. The basal lamina is the extracellular matrix surrounding the muscle fiber, made up largely of collagen, that connects each muscle fiber to its neighbors and helps them contract in unison.

An antagonist is defined as the muscle that strecthes when another muscle (the agonist) is contracting. When the antagonist contracts, it will stretch the agonist and move the bone in the opposite direction.

The biceps brachii is responsible for flexion of the forearm, while the triceps brachii is responsible for the extension of the forearm. As a result, we say that the triceps brachii is the antagonist of the biceps brachii.

Synergistic muscles assist agonists by properly positioning the insertion bone or stabilizing the origin bone. This cooperation by multiple muscles allows for better movement and posture. Since the temporalis assists in raising the jaw with the masseter, we say that the temporalis is the synergist of the masseter.

During muscle contraction, the H zone and I band contract, decreasing in length. The A band never changes in length. Also, while actin and myosin myofilaments slide over each other, their length does not change either.

There are three primary types of muscle tissue: skeletal, smooth, and cardiac.

Skeletal muscle and cardiac muscle are highly organized, with their contractile filaments arranged into sarcomeres. This organization results in a "striped" look on the cells, known as striations. Smooth muscle contains the same contractile filaments, but lacks the sort of highly organized structure found in the other two muscle types. As a result, smooth muscle is not striated.

Smooth muscle and cardiac muscle are generally mononucleate, meaning that each cell has only on nucleus. In contrast, skeletal muscle cells contain multiple nuclei.

The correct answer is that skeletal muscle is striated and contains multiple nuclei per cell.

The sarcolemma is the specialized cell membrane of a myocyte, or muscle cell. It performs all of the functions of a non-specialized plasmolemma, and forms T-tubules, which are important for muscle contraction.

The primary functions of muscle tissue are motion and locomotion (movement in relation to the body, and movement of the entire body). Muscle is also responsible for the shiver response, used in thermoregulation. Finally, smooth muscles move substances through the body in the process known as peristalsis.

Leverage is a function primarily accomplished by bone.

None of the answer options satisfy all of the criteria given in the question. Cardiac muscle cells have intercalated discs, but are mononucleate.